UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ![]() | Submission Date | |
Q5JFJ4 | Unreviewed | RecJ-like exonuclease, containing OB-fold nucleic acid-binding domains | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)). | 29209094 | Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef. | [Function] | Protein/gene_name: TK0155;HAN;Hef-associated nuclease. Function: Has a single-strand specific 3' to 5' exonuclease activity, which is stimulated in the presence of Hef. Additional Annotation: RecJ-family protein. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-9 | |
Q8TZE0 | Unreviewed | Single-stranded-DNA-specific exonuclease RecJ | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1). | 23605041 | RecJ-like protein from Pyrococcus furiosus has 3'-5' exonuclease activity on RNA: implications for proofreading of 3'-mismatched RNA primers in DNA replication. | [Function] | Protein/gene_name: PF2055;PfRecJ;RecJ-like protein. Function: Has a potential role in proofreading 3'-mismatched ribonucleotides. Hydrolyzes single-stranded RNA and the RNA strand of RNA/DNA hybrids in the 3'-5' direction. Additional Annotation: The 3' exonuclease activity is dependent on the divalent metal ion Mn(2+), with an optimal concentration range from 0.1 to 0.5 mM. Exhibits highest activity at pH range from 7.0 to 7.5, and at 70 degrees Celsius. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-9 | |
A0A524EN15 | Unreviewed | UPF0215 protein EU537_03525 | Thorarchaeota archaeon (strain OWC). | 39426726 | DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates. | [Function] | Protein/gene_name: ThorEndo_dU;Endonuclease dU;Endo_dU. Function: Cleaves on the 3'-side of dU on DNA. Additional Annotation: DUF99 family protein. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-7 | |
A0A524DLA3 | Unreviewed | UPF0215 protein EU540_03240 | Promethearchaeota archaeon. | 39426726 | DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates. | [Function] | Protein/gene_name: LokiEndo_dU;Endonuclease dU;Endo_dU. Function: Cleaves on the 3'-side of dU on DNA. Additional Annotation: DUF99 family protein. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-7 | |
A0A534D4D0 | Unreviewed | DUF99 family protein | Gammaproteobacteria bacterium. | 39426726 | DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates. | [Function] | Protein/gene_name: GmEndo_dU;Endonuclease dU;Endo_dU. Function: Cleaves on the 3'-side of dU on DNA. Additional Annotation: DUF99 family protein. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-7 | |
O28839 | Reviewed | UPF0215 protein AF_1433 | Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16). | 39426726 | DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates. | [Function] | Protein/gene_name: AfuEndo_dU;Endonuclease dU;Endo dU. Function: Cleaves on the 3'-side of dU on DNA. Additional Annotation: DUF99 family protein. Active in temperatures ranging from 4 to 55 degrees Celsius. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-2-7 | |
Q80YT5 | Reviewed | Spermatogenesis-associated protein 20 | Mus musculus (Mouse). | 29247744 | Disruption of Ssp411 causes impaired sperm head formation and male sterility in mice. | [Function][Subcellular location][Expression][Interaction] | Anonymous | Anonymous | 2025-2-7 | ||
Q8IWD5 | Reviewed | Major facilitator superfamily domain-containing protein 6-like | Homo sapiens (Human). | 38909778 | Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice. | [Function][Subcellular location][Expression][Interaction] | Anonymous | Anonymous | 2025-2-7 | ||
Q8TBZ2 | Reviewed | MYCBP-associated protein | Homo sapiens (Human). | 39704931 | Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice. | [Function][Subcellular location][Expression][Interaction] | Protein/gene_name: MYCBPAP. Function: Essential role in normal spermatogenesis. Disease: Male infertility. | Anonymous | Anonymous | 2025-2-7 | |
Q80YT5 | Reviewed | Spermatogenesis-associated protein 20 | Mus musculus (Mouse). | 39091129 | Application of genome tagging technology in elucidating the function of sperm-specific protein 411 (Ssp411). | [Subcellular location][Expression] | Anonymous | Anonymous | 2025-2-7 | ||
O18330 | Reviewed | Major royal jelly protein 1 | Apis mellifera (Honeybee). | 27652566 | Royalactin is not a royal making of a queen. | [Function] | Protein/gene_name: MRJP1. Function: Does not induce queen differentiation in honey bee larvae. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7RAT9 | Unreviewed | O-acyltransferase | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: acat. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees and forager bees but not in nurse bees. Expression was significantly higher in freshly hatched bees compared to nurse and forager bees. Of all sterol metabolism genes that were analysed in the publication, this one was the one with the lowest expression. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7GZ33 | Unreviewed | NPC intracellular cholesterol transporter 1 isoform X3 | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: npc1 alpha. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees and forager bees and in mandibular glands of nurse bees with expression being significantly higher in freshly hatched bees compared to nurse and forager bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7H2V0 | Unreviewed | Sterol carrier protein 2 | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: scp-2. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees with expression being significantly higher in freshly hatched bees compared to nurse and forager bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7R3E4 | Unreviewed | MD-2-related lipid-recognition protein | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: NPC intracellular cholesterol transporter;npc2â1. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees. Among the four NPC intracellular cholesterol transporter genes in A.mellifera (Gene IDs: 409187, 551922, 724386, 725038), this one showed medium expression in the mentioned glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7TFS9 | Unreviewed | NPC intracellular cholesterol transporter 2 homolog a | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: npc2â2. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees. Among the four NPC intracellular cholesterol transporter genes in A.mellifera (Gene IDs: 409187, 551922, 724386, 725038), this one showed medium expression in the mentioned glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7G1N6 | Unreviewed | NPC intracellular cholesterol transporter 2 | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: npc2â3. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees. Among the four NPC intracellular cholesterol transporter genes in A.mellifera (Gene IDs: 409187, 551922, 724386, 725038), this one showed the lowest expression in the mentioned glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M7FXY2 | Unreviewed | NPC intracellular cholesterol transporter 2 homolog a | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: npc2â4. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees. Among the four NPC intracellular cholesterol transporter genes in A.mellifera (Gene IDs: 409187, 551922, 724386, 725038), this one showed the highest expression in the mentioned glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
Q8ISL8 | Reviewed | Apisimin | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: Apisimin. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees with the expression being much higher in hypopharyngeal glands compared to mandibular glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
O18330 | Reviewed | Major royal jelly protein 1 | Apis mellifera (Honeybee). | 38567629 | Expression of honey bee (Apis mellifera) sterol homeostasis genes in food jelly producing glands of workers. | [Expression] | Protein/gene_name: MRJP1. Additional Annotation: Expression detected in hypopharyngeal and mandibular glands of freshly-emerged bees, nurse bees and forager bees with the expression being much higher in hypopharyngeal glands compared to mandibular glands. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
O18330 | Reviewed | Major royal jelly protein 1 | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Additional Annotation: Detected in hypopharyngeal glands and brains in freshly-emerged and nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
O77061 | Reviewed | Major royal jelly protein 2 | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Additional Annotation: Detected in hypopharyngeal glands and brains in freshly-emerged and nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
Q17060 | Reviewed | Major royal jelly protein 3 | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Additional Annotation: Detected in hypopharyngeal glands and brains in freshly-emerged and nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
Q17061 | Reviewed | Major royal jelly protein 4 | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Additional Annotation: Detected in hypopharyngeal glands and brains of nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
O97432 | Reviewed | Major royal jelly protein 5 | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Additional Annotation: Detected in hypopharyngeal glands and brains of nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
Q8ISL8 | Reviewed | Apisimin | Apis mellifera (Honeybee). | 29551410 | How Honeybees Defy Gravity with Royal Jelly to Raise Queens. | [Function] | Protein/gene_name: Apisimin. Additional Annotation: Polymerizes into long fibrous structures in complex with MRJP1 (O18330). These fibrils form at the native pH of royal jelly and determine royal jelly viscosity. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
O18330 | Reviewed | Major royal jelly protein 1 | Apis mellifera (Honeybee). | 29551410 | How Honeybees Defy Gravity with Royal Jelly to Raise Queens. | [Function][Subcellular location] | Protein/gene_name: Major royal jelly protein 1. Additional Annotation: Polymerizes into long fibrous structures in complex with apisimin (Q8ISL8). These fibrils form at the native pH of royal jelly and determine royal jelly viscosity. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M6W880 | Unreviewed | Bee-milk protein | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Protein/gene_name: Major royal jelly protein 9. Additional Annotation: Detected in hypopharyngeal glands of nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A7M6W5F9 | Unreviewed | Bee-milk protein | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Protein/gene_name: Major royal jelly protein 7. Additional Annotation: Detected in hypopharyngeal glands and brains of nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
A0A8U0WQ84 | Unreviewed | Bee-milk protein | Apis mellifera (Honeybee). | 31410279 | The rise and fall of major royal jelly proteins during a honeybee (Apis mellifera) workers' life. | [Subcellular location][Expression][Sequence] | Protein/gene_name: Major royal jelly protein 6. Additional Annotation: Detected in hypopharyngeal glands in nurse bees. | Anja Buttstedt | 0000-0003-2299-7000 | 2025-2-5 | |
Q83BW7 | Unreviewed | Hypothetical membrane associated protein | Coxiella burnetii (strain RSA 493 / Nine Mile phase I). | 39333627 | A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets. | [Function][Subcellular location][Interaction] | Protein/gene_name: CBU1370;CbEPF1;Coxiella burnetii Effector protein with FFAT motifs. Function: Influences host lipid droplet metabolism. Additional Annotation: Subcellular location: Secreted. Localizes to host cell endoplasmic reticulum and lipid droplets. Interacts with VAMPâassociated proteins (VAPs) using FFAT motifs and mediates inter-organelle contact sites between endoplasmic reticulum and lipid droplets. | Rajendra angara | 0000-0001-5449-7305 | 2025-1-31 | |
P94378 | Reviewed | Putative 3-methyladenine DNA glycosylase | Bacillus subtilis (strain 168). | 27698084 | Aag Hypoxanthine-DNA Glycosylase Is Synthesized in the Forespore Compartment and Involved in Counteracting the Genotoxic and Mutagenic Effects of Hypoxanthine and Alkylated Bases in DNA during Bacillus subtilis Sporulation. | [Function][Subcellular location][Expression] | Protein/gene_name: Aag;Alkyl adenine glycosylase. Function: Protects the genome of the developing organism's sporangia from the cytotoxic and genotoxic effects of base deamination and alkylation. May potentially interfere with spore morphogenesis. Additional Annotation: Exhibits a forespore-specific pattern of gene expression during sporulation. Expressed primarily during spore development. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-31 | |
P29372 | Reviewed | DNA-3-methyladenine glycosylase | Homo sapiens (Human). | 14729667 | The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. | [Function] | Protein/gene_name: AAG;Aag. Function: Cleaves 1,N6-ethenoadenine. Hypoxanthine excision. Additional Annotation: Kinetic parameters: KM=23 nM with ethenoadenine as substrate. kcat=0.13 min(-1) for ethenoadenine. KM=5.3 nM for hypoxanthine as substrate. kcat=0.005 min(-1) for hypoxanthine removal. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-31 | |
P94378 | Reviewed | Putative 3-methyladenine DNA glycosylase | Bacillus subtilis (strain 168). | 14729667 | The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. | [Function] | Protein/gene_name: BAag;aag;3-Methyladenine DNA Glycosylase. Function: A DNA glycosylase that releases 3-alkylated purines and hypoxanthine, and the cyclic etheno adduct 1,N6-ethenoadenine from DNA. Has an important role in preventing the mutagenic effects of deaminated purines and cyclic etheno adducts, and a minor role in the repair of DNA alkylation damage. Additional Annotation: Kinetic parameters: KM=21 nM with ethenoadenine as substrate. kcat=0.1 min(-1) for ethenoadenine. KM=5.0 nM for hypoxanthine as substrate. kcat= 0.053 min(-1) for hypoxanthine removal. No activity toward 8-oxoG, formamidopyrimidine (faPy), or abasic sites. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-31 | |
P94378 | Reviewed | Putative 3-methyladenine DNA glycosylase | Bacillus subtilis (strain 168). | 27698084 | Aag Hypoxanthine-DNA Glycosylase Is Synthesized in the Forespore Compartment and Involved in Counteracting the Genotoxic and Mutagenic Effects of Hypoxanthine and Alkylated Bases in DNA during Bacillus subtilis Sporulation. | [Function][Subcellular location][Expression] | Anonymous | Anonymous | 2025-1-31 | ||
P94378 | Reviewed | Putative 3-methyladenine DNA glycosylase | Bacillus subtilis (strain 168). | 14729667 | The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. | [Function] | Anonymous | Anonymous | 2025-1-31 | ||
A8RZR5 | Unreviewed | FAD-binding PCMH-type domain-containing protein | Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351) (Clostridium bolteae). | 39856097 | Diet-derived urolithin A is produced by a dehydroxylase encoded by human gut Enterocloster species. | [Function][Expression][Sequence] | Protein/gene_name: UcdC;ucdC;Urolithin C dehydroxylase C. Function: A part of the UcdCFO complex that dehydroxylates the 9-position hydroxyl group of urolithins, e.g., urolithin C, urolithin M5, urolithin M6, urolithin D, isourolithin A. Specific to this position. Predicted to bind FAD. Additional Annotation: Belongs to xanthine dehydrogenase/oxidase family proteins. Expression is induced by its substrates, e.g., urolithin C, urolithin M6 and isourolithin A. | Reilly Pidgeon | 0000-0002-7372-526X | 2025-1-29 | |
A8RZR3 | Unreviewed | 2Fe-2S ferredoxin-type domain-containing protein | Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351) (Clostridium bolteae). | 39856097 | Diet-derived urolithin A is produced by a dehydroxylase encoded by human gut Enterocloster species. | [Function][Expression][Sequence] | Protein/gene_name: UcdF;ucdF;Urolithin C dehydroxylase F. Function: A part of the UcdCFO complex that dehydroxylates the 9-position hydroxyl group of urolithins, e.g., urolithin C, urolithin M5, urolithin M6, urolithin D, isourolithin A. Specific to this position. Predicted to bind two 2Fe-2S clusters. Additional Annotation: Belongs to xanthine dehydrogenase/oxidase family proteins. Expression is induced by its substrates, e.g., urolithin C, urolithin M6 and isourolithin A. | Reilly Pidgeon | 0000-0002-7372-526X | 2025-1-29 | |
A8RZR2 | Unreviewed | Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead domain-containing protein | Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351) (Clostridium bolteae). | 39856097 | Diet-derived urolithin A is produced by a dehydroxylase encoded by human gut Enterocloster species. | [Function][Expression][Sequence] | Protein/gene_name: UcdO;ucdO. Function: A part of the UcdCFO complex that dehydroxylates the 9-position hydroxyl group of urolithins, e.g., urolithin C, urolithin M5, urolithin M6, urolithin D and isourolithin A. Specific to this position. Predicted to bind a molybdopterin cytosine dinucleotide cofactor. Additional Annotation: Belongs to xanthine dehydrogenase/oxidase family proteins. Expression of is induced by its substrates, e.g., urolithin C, urolithin M6, isourolithin A. | Reilly Pidgeon | 0000-0002-7372-526X | 2025-1-29 | |
P18035 | Reviewed | Protein TrbB | Escherichia coli (strain K12). | 39131116 | Structural insights into the disulfide isomerase and chaperone activity of TrbB of the F plasmid type IV secretion system. | [Function][Interaction][Structure][Sequence] | Arnold J Apostol | 0009-0007-8791-0339 | 2025-1-28 | ||
A0A1V2JN15 | Unreviewed | Serine hydroxymethyltransferase | Pseudomonas azotoformans. | 38519422 | Biosynthesis of Strained Amino Acids by a PLP-Dependent Enzyme through Cryptic Halogenation. | [Function][Sequence] | Protein/gene_name: PazB. Function: PLP-dependent, intramolecular cyclization of L-4-chlorolysine to pazamine ((1R,2R)-2-(2-aminoethyl)cyclopropane-1-carboxylic acid). | Max Bernstein Sosa | 0009-0008-8230-6535 | 2025-1-28 | |
C4M8S6 | Unreviewed | Acid phosphatase, putative | Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM). | 33671604 | Structure-Function Relationship Study of a Secretory Amoebic Phosphatase: A Computational-Experimental Approach. | [Function][Structure] | Marco A. Ramos-Ibarra | 0000-0002-8950-2079 | 2025-1-26 | ||
V9NT62 | Unreviewed | A17L | Monkeypox virus. | 39861882 | Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance. | [Function][Pathology & Biotech][PTM / Processing][Interaction] | Protein/gene_name: MPXVgp127. Additional Annotation: A myristoylated protein. The penultimate amino terminus glycine is a target for myristoylation. Inhibition of myristoylation will target this protein for degradation via proteasome pathway. | Anonymous | Anonymous | 2025-1-26 | |
Q3I7N8 | Unreviewed | MPXV-COP-073 | Monkeypox virus. | 39861882 | Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance. | [Function][Pathology & Biotech][PTM / Processing][Interaction] | Protein/gene_name: MPXVgp079. Additional Annotation: A myristoylated protein. The penultimate amino terminus glycine is a target for myristoylation. Inhibition of myristoylation will target this protein for degradation via proteasome pathway. | Anonymous | Anonymous | 2025-1-26 | |
Q5IXU5 | Unreviewed | IMV membrane protein | Monkeypox virus. | 39861882 | Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance. | [Function][Pathology & Biotech][Interaction] | Protein/gene_name: MPXVgp080. Additional Annotation: A myristoylated protein. The penultimate amino terminus glycine is a target for myristoylation. Inhibition of myristoylation will target this protein for degradation via proteasome pathway. | Anonymous | Anonymous | 2025-1-26 | |
Q6LYG7 | Unreviewed | MCM family related protein | Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL). | 28516862 | Non-essential MCM-related proteins mediate a response to DNA damage in the archaeon Methanococcus maripaludis. | [Function] | Protein/gene_name: McmD;MMP1024;Minichromosome maintenance protein D. Function: Mediates a response to DNA damage. Additional Annotation: Gene deletion mutant is substantially more sensitive to DNA damage by UV and ionizing radiation than the wild type. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-24 | |
Q6LZ81 | Unreviewed | MCM family related protein | Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL). | 28516862 | Non-essential MCM-related proteins mediate a response to DNA damage in the archaeon Methanococcus maripaludis. | [Function] | Protein/gene_name: McmC;MMP0748;Minichromosome maintenance protein C. Function: Mediates a response to DNA damage. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-24 | |
Q6M003 | Unreviewed | MCM family related protein | Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL). | 28516862 | Non-essential MCM-related proteins mediate a response to DNA damage in the archaeon Methanococcus maripaludis. | [Function] | Protein/gene_name: McmB;MMP0470;Minichromosome maintenance protein B. Function: Shows robust DNA helicase activity in vitro. Mediates a response to DNA damage. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-24 | |
Q6M187 | Unreviewed | DNA replication protein MCM family putative | Methanococcus maripaludis (strain DSM 14266 / JCM 13030 / NBRC 101832 / S2 / LL). | 28516862 | Non-essential MCM-related proteins mediate a response to DNA damage in the archaeon Methanococcus maripaludis. | [Function] | Protein/gene_name: McmA;MMP0030;Minichromosome maintenance protein A. Function: Shows robust DNA helicase activity in vitro. Additional Annotation: Essential gene. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-24 | |
Q4JAB6 | Unreviewed | Conserved Archaeal protein | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770). | 27821767 | Archaeal orthologs of Cdc45 and GINS form a stable complex that stimulates the helicase activity of MCM. | [Function][Interaction] | Protein/gene_name: Gins23;Saci_0901. Function: Together with Cdc45 and Gins15, forms a stable complex that stimulates the helicase activity of MCM. | Minna Lehvaslaiho | 0000-0002-8506-7364 | 2025-1-24 |