UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ![]() | Submission Date | |
D4GP40 | Reviewed | D-xylonate dehydratase | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii). | 27297879 | Key Enzymes of the Semiphosphorylative Entner-Doudoroff Pathway in the Haloarchaeon Haloferax volcanii: Characterization of Glucose Dehydrogenase, Gluconate Dehydratase, and 2-Keto-3-Deoxy-6-Phosphogluconate Aldolase. | [Function][Pathology & Biotech] | Protein/gene_name: XAD; Xylonate dehydratase; HVO_B0038A. Function: Catalyzes the dehydration of xylonate to 2-dehydro-3-deoxy-D-arabinonate. Additional Annotation: Catalyzes the dehydration of xylonate and gluconate at similar efficiencies (data from PMID:19584053). XAD allows the growth of a GAD deletion mutant on glucose, but the initial lag phase was 150 hours. The GAD/XAD double-deletion mutant does not grow on glucose. | Friedhelm Pfeiffer | 0000-0003-4691-3246 | 2021-3-29 |