UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
A2T3P0 | Reviewed | Non-structural protein 2 | Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)). | 34615715 | Structural basis of rotavirus RNA chaperone displacement and RNA annealing. | [Function][Structure] | Function: RNA folding chaperone (GO:0140691). Additional Annotation: Strain= SA11. | Ralf Stephan | 0000-0002-4650-631X | 2022-12-8 | |
A2T3P0 | Reviewed | Non-structural protein 2 | Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)). | 32461314 | A Genetically Engineered Rotavirus NSP2 Phosphorylation Mutant Impaired in Viroplasm Formation and Replication Shows an Early Interaction between vNSP2 and Cellular Lipid Droplets. | [Interaction] | Additional Annotation: When phosphorylated at Ser-313, interacts with phosphorylated PLIN1 associated with liquid droplets. Strain=SA11 4F G3P6[1]. | Ralf Stephan | 0000-0002-4650-631X | 2022-12-5 | |
A2T3P0 | Reviewed | Non-structural protein 2 | Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)). | 30509975 | Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories. | [Subcellular location][Interaction][PTM / Processing] | Additional Annotation: Phosphorylated at Ser-313 by CK1. After phosphorylation, together with NSP5 and VP2 forms core of viroplasm viral factory (GO:0039716). Strain=SA11 4F G3P6. | Ralf Stephan | 0000-0002-4650-631X | 2022-12-1 | |
A2T3P0 | Reviewed | Non-structural protein 2 | Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)). | 24198401 | A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly. | [Subcellular location] | Additional Annotation: After translation NSP2 disperses in the host cytosol. Strain=SA11-4F. | Ralf Stephan | 0000-0002-4650-631X | 2022-12-1 | |
A2T3P0 | Reviewed | Non-structural protein 2 | Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)). | 12072508 | Analysis of a temperature-sensitive mutant rotavirus indicates that NSP2 octamers are the functional form of the protein. | [Interaction] | Additional Annotation: Forms a homooctamer. Strain=SA11. | Ralf Stephan | 0000-0002-4650-631X | 2022-12-1 |