UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
D3Z596 | Unreviewed | Insulin II | Mus musculus (Mouse). | 37967211 | Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing. | [Expression] | Additional Annotation: Expression of alternatively spliced INS2 D3Z596 in pancreatic islets. | James Michael Fulcher | 0000-0001-9033-3623 | 2024-10-3 | |
D3Z596 | Unreviewed | Insulin II | Mus musculus (Mouse). | 36266275 | Combining mass spectrometry and machine learning to discover bioactive peptides. | [Function][PTM / Processing][Expression][Sequence] | Function: Alternative splicing decouples B- and A-chain configuration, to only form B-chain and a new reading frame creating D-peptide. Additional Annotation: Splicing event only observed in pancreas. Comments: Alternative splicing event creating a new peptide (D-peptide) in insulin-2. Mass spectrometry verification of the peptide. | Christian Toft Madsen | 0000-0003-3268-5350 | 2022-11-10 |