UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
O00429 | Reviewed | Dynamin-1-like protein | Homo sapiens (Human). | 30531964 | Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission. | [Function] | Protein/gene_name: Dynamin-1-like protein;DNM1L. Function: Necessary for mitochondrial and peroxisomal division. Sufficient for membrane fission. Organizes into membrane-associated scaffolds that wrap around a tubule and utilizes GTP hydrolysis to constrict and sever the tubule. Additional Annotation: Recruitment to scission sites can be through cardiolipin or through membrane receptors like MFF. | Anonymous | Anonymous | 2023-8-1 |