UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
P0DTD1 | Reviewed | Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2). | 33202171 | Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential. | [Function][Structure][Sequence] | Function: The S2-MacroD domain functions as (ADP-ribosyl)hydrolase of automodified PARP14 and PARP14 targets. Disease: COVID-19. Additional Annotation: Characterization of the S2-MacroD domain which corresponds to the prosite annotation Macro (PROSITE-ProRule:PRU00490). Other publications call this region X domain or Mac1. | Johannes Gregor Matthias Rack | 0000-0001-8341-6439 | 2020-11-20 |