UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
P23229 | Reviewed | Integrin alpha-6 | Homo sapiens (Human). | 29759989 | Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer. | [Function][Subcellular location][Interaction] | Protein/gene_name: Integrin a6b1. Function: Integrin a6b1 is trafficked specifically by Rab11-FIP5 proteins. The internalization and recycling of a6 integrin by Rab11-FIP5 is specific for the alpha 6 subunit and not observed with a3 integrin or other unrelated type I membrane spanning receptors. Disease: Prostate Cancer. Additional Annotation: Integrin a6 localizes to early endosomes and is recycled onto the cell surface by Rab11-FIP5. | Anne Cress | 0000-0001-6194-0061 | 2020-3-8 |