UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
P35222 | Reviewed | Catenin beta-1 | Homo sapiens (Human). | 24744147 | O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. | [Function][Subcellular location][Pathology & Biotech][PTM / Processing][Interaction] | Protein/gene_name: Beta-catenin. Function: Beta-catenin is involved in cell signaling and cell proliferation. It is expressed at the inner face of plasma membrane (it is part of the adherens junctions) and it associated to TCF to manage cell cycle. Disease:Epithelial cancers. Additional Annotation: In this publication we have mapped 4 sites of O-GlcNAcylation at Ser-23, Thr-40, Thr-41 and Thr-112. | Tony Lefebvre | 0000-0001-9883-2240 | 2019-10-14 |