UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
Q13428 | Reviewed | Treacle protein | Homo sapiens (Human). | 37586369 | An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates. | [Function][Subcellular location] | Protein/gene_name: TCOF1;Treacle. Function: Serves as a scaffold protein necessary for the formation of the fibrillar center of the nucleolus through self-assembly. Additional Annotation: May underlie the evolutionary emergence of the fibrillar center; its emergence correlates with emergence of the fibrillar center across species, and its introduction into an organism lacking the fibrillar center is sufficient for de novo formation of the fibrillar center. Subcellular location: Nucleolar fibrillar center. | Anonymous | Anonymous | 2024-8-23 |