UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
Q8MMJ7 | Reviewed | Cytotoxic linear peptide IsCT | Opisthacanthus madagascariensis (Scorpion). | 31642159 | IsCT-based analogs intending better biological activity. | [Function] | Additional Annotation: Five engineered IsCT1 (ILGKIWEGIKSLF)-based analogs had antimicrobial and hemolytic activity. Note: Circular dichroism analysis. | Cyntia Silva Oliveira | 0000-0003-2049-7627 | 2024-1-27 | |
Q8MMJ7 | Reviewed | Cytotoxic linear peptide IsCT | Opisthacanthus madagascariensis (Scorpion). | 34463484 | Synthetic Peptide Derived from Scorpion Venom Displays Minimal Toxicity and Anti-infective Activity in an Animal Model. | [Function] | Additional Annotation: Engineered peptide IsCT1-NH2 has antimicrobial, anti-infective and hemolytic activity. A simple method based on net charge tuning may be used to turn highly toxic venom-derived peptides into viable therapeutics. | Cyntia Silva Oliveira | 0000-0003-2049-7627 | 2024-1-27 |