UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
Q8WXG1 | Reviewed | S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 | Homo sapiens (Human). | 29925952 | A naturally occurring antiviral ribonucleotide encoded by the human genome. | [Function] | Protein/gene_name: Viperin; RSAD2. Function: Converts cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP), via a SAM-dependent radical mechanism. Has antiviral activity by leading to premature chain termination during RNA virus replication. | Daniel Haft | 0000-0001-8101-4938 | 2020-9-27 |