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UniProt AC
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Q9H2V7ReviewedProtein spinster homolog 1 Homo sapiens (Human).37075117An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.[Function][Subcellular location][Pathology & Biotech]Protein/gene_name: SPNS1.
Function: Proton-dependent lysosomal transporter for lysophospholipids, in particular lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE). Exports LPC and LPE from the lysosomal lumen to the cytosol. Plays a critical role in recycling choline-containing lipids and becomes essential for cell survival when the availability of free choline in the environment is limited.
AnonymousAnonymous2023-5-11