UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
Q9UD71 | Reviewed | Protein phosphatase 1 regulatory subunit 1B | Homo sapiens (Human). | 30552871 | Darpp-32 and t-Darpp protein products of PPP1R1B: Old dogs with new tricks. | [Function] | Protein/gene_name: T-Darpp; PPP1R1B. Function: Confers trastuzumab resistance in breast cancer cells. Disease: Gastric, breast, colon, esophagus, lung and prostate cancers. Additional Annotation: Phosphorylated by CDK1. | Jamil Momand | 0000-0003-2017-9733 | 2022-11-17 | |
Q9UD71 | Reviewed | Protein phosphatase 1 regulatory subunit 1B | Homo sapiens (Human). | 28904862 | t-Darpp is an elongated monomer that binds calcium and is phosphorylated by cyclin-dependent kinases 1 and 5. | [PTM / Processing] | Additional Annotation: Binds calcium. | Jamil Momand | 0000-0003-2017-9733 | 2022-11-17 |