UniProt AC | UniProt Status | Protein Name | Organism | PMID | Article Title | Category | Annotation | Contributor | ORCID | Submission Date | |
Q9VW15 | Reviewed | Histone-lysine N-methyltransferase ash1 | Drosophila melanogaster (Fruit fly). | 23442797 | The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila. | [Function] | Function: Data strongly favor a global coactivator function of ASH1 and FSH during transcription, as opposed to the notion that TrxG proteins impede inappropriate PcG-mediated silencing, but are dispensable elsewhere. Additional Annotation: Genome-wide maps of ASH1 and FSH chromatin occupancy show localization at PREs, active and PcG-repressed genes. | Tobias Kockmann | 0000-0002-1847-885X | 2020-4-15 |